Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Flupentixol

Flupentixol is an orally active D1/D2 dopamine receptor antagonist and new PI3K inhibitor (PI3Kα IC50=127 nM) . Flupentixol shows anti-proliferative activity to cancer cells and induces apoptosis. Flupentixol can also be used in schizophrenia, anxiolytic and depressive research[1][2][3].

Product Specifications

CAS Number

2709-56-0

Product Name Alternative

Flupenthixol

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Apoptosis; Dopamine Receptor; PI3K

Type

Reference compound

Related Pathways

Apoptosis; GPCR/G Protein; Neuronal Signaling; PI3K/Akt/mTOR

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/flupentixol.html

Solubility

10 mM in DMSO

Smiles

OCCN1CCN(CC/C=C2C3=C(SC4=C/2C=CC=C4)C=CC(C(F)(F)F)=C3)CC1

Molecular Formula

C23H25F3N2OS

Molecular Weight

434.52

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Yonar D, et al. Effect of cis- (Z) -flupentixol on DPPC membranes in the presence and absence of cholesterol. Chem Phys Lipids. 2016 Jun;198:61-71.|[2]Ruhrmann S, et al. Efficacy of flupentixol and risperidone in chronic schizophrenia with predominantly negative symptoms. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Jun 30;31 (5) :1012-22.|[3]Chao Dong, et al. The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer. Int J Biol Sci. 2019 Jun 2;15 (7) :1523-1532.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

D1 Receptor; D2 Receptor; PI3Kα

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Erwinia amylovora TaqMan Probe/Primer and Control Set
TM35110 100 Reactions

Erwinia amylovora TaqMan Probe/Primer and Control Set

Sign In for Pricing
View Details
Human PRPF4B activation kit by CRISPRa
GA105930 1 Kit

Human PRPF4B activation kit by CRISPRa

Sign In for Pricing
View Details
2-(3,4-Dihydro-2,4-dioxo-1(2H)-quinazolinyl)benzoic Acid
TRC-D450135-25MG 25 mg

2-(3,4-Dihydro-2,4-dioxo-1(2H)-quinazolinyl)benzoic Acid

Sign In for Pricing
View Details
6-HEX phosphoramidite [5'-Hexachlorofluorescein phosphoramidite]
6026-AAT 100 µmole

6-HEX phosphoramidite [5'-Hexachlorofluorescein phosphoramidite]

Sign In for Pricing
View Details
Histidase (HAL) (NM_002108) Human Recombinant Protein
TP311651M 100 µg

Histidase (HAL) (NM_002108) Human Recombinant Protein

Sign In for Pricing
View Details
Rat IL-2 Recombinant Rabbit Monoclonal Antibody [PS01-89] - BSA and Azide free (Detector)
HA721613 100 µL

Rat IL-2 Recombinant Rabbit Monoclonal Antibody [PS01-89] - BSA and Azide free (Detector)

Sign In for Pricing
View Details