DHX9-IN-16
DHX9-IN-16 (208) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.125 μM in DHX9 cellular target engagement. Used in cancer research[1].
Product Specifications
CAS Number
2973397-48-5
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-16.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C2=NC=C(C=N2)OCC)C(C)=C1)NC3=CC(Cl)=CC(NS(=O)(C)=O)=C3
Molecular Formula
C19H20ClN5O4S
Molecular Weight
449.91
References & Citations
[1]Matthew H, et al.Matthew H, et al. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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