DHX9-IN-17
DHX9-IN-17 (186) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.161 μM in DHX9 cellular target engagement. Used in cancer research[1].
Product Specifications
CAS Number
2973397-26-9
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-17.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C2=NC=CC=C2OCC3=CC(F)=CN=C3)N=C1)NC4=CC(NS(=O)(C)=O)=CC(Cl)=C4
Molecular Formula
C22H18ClFN6O4S
Molecular Weight
516.93
References & Citations
[1]Matthew H, et al. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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