DHX9-IN-14
DHX9-IN-14 (161) is a RNA helicase DHX9 inhibitor, with an EC50 of 3.4 μM in DHX9 cellular target engagement. Used in cancer research[1].
Product Specifications
CAS Number
[2973747-90-7]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-14.html
Solubility
10 mM in DMSO
Smiles
CN1C=C(C=C1C2=NC=C(C=C2F)F)C(NC3=CC(NS(C)(=O)=O)=CC=C3)=O
Molecular Formula
C18H16F2N4O3S
Molecular Weight
406.41
References & Citations
[1]Matthew H. Daniels, et al. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023158795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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