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DHX9-IN-11

DHX9-IN-11 (469) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.0838 μM in DHX9 cellular target engagement. Used in cancer research[1].

Product Specifications

CAS Number

2973402-91-2

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dhx9-in-11.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C)C(C2=C(F)C=C(N3CCC(F)(CC3)F)C=N2)=C1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4

Molecular Formula

C23H23ClF3N5O3S

Molecular Weight

541.97

References & Citations

[1]Matthew H, et al. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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