DHX9-IN-7
DHX9-IN-7 (550) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.105 μM in DHX9 cellular target engagement. Used in cancer research[1].
Product Specifications
CAS Number
2973400-87-0
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=NC=C(C(F)(F)F)C=C2OC)=C(C)S1)NC3=CC(Cl)=CC(NS(=O)(C)=O)=C3
Molecular Formula
C20H17ClF3N3O4S2
Molecular Weight
519.94
References & Citations
[1]Matthew H, et al. Inhibitors of rna helicase dhx9 and uses thereof. Patent WO2023154519.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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