KDRLKZ-3
Product Specifications
UNSPSC Description
KDRLKZ-3 is a selective E3 ligase. KDRLKZ-3 is a ligand for KLHDC2 with a IC50 value of 4.1 μM in the alphaLISA experiment[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/kdrlkz-3.html
Solubility
10 mM in DMSO
Smiles
O=C(OCCOC)N(CC1)CC(N(C2=O)C3=CN(C(C=C3)=O)CC(N)=O)=C1C=C2C(C)CC
Molecular Weight
458.51
References & Citations
[1]Hickey CM, et al. Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat Struct Mol Biol. 2024 Jan 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157560/KDRLKZ-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157560/
Clinical Information
No Development Reported
Curated Selection
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