KDRLKZ-1
Product Specifications
UNSPSC Description
KDRLKZ-1 is a KLHDC2 ligand (Kd = 0.36 μM), with IC50s of 0.21 μM and 0.31 μM in alphaLISA and time-resolved fluorescence resonance energy transfer (TR-FRET) displacement assays[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/kdrlkz-1.html
Solubility
10 mM in DMSO
Smiles
CCC(C1=CC2=C(N(C1=O)C3=CN(C(C=C3)=O)CC(O)=O)CN(CC2)C(OCCOC)=O)C
Molecular Weight
459.49
References & Citations
[1]Hickey CM, et al. Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat Struct Mol Biol. 2024 Jan 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157558/KDRLKZ-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157558/
Clinical Information
No Development Reported
Curated Selection
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