BPP-2
Product Specifications
UNSPSC Description
BPP-2 is a GHSR ligand with an F element. Using 18F isotope labeling BPP-2, a PET probe targeting GHSR can be obtained. The binding affinity Ki of 18F-BPP-2 for GHSR is 274 nM[1].
Target Antigen
GHSR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bpp-2.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(N)=C(C(COCC2=CC=CC=C2)=N1)C3=CC=C(C=C3)NCC4=CC=C(C=C4)OCCF
Molecular Weight
473.54
References & Citations
[1]Saito H, et al. Synthesis and biological evaluation of novel 18F-labeled 2,4-diaminopyrimidine derivatives for detection of ghrelin receptor in the brain. Bioorg Med Chem Lett. 2024 Jan 20:129625.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157556/BPP-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157556/
Clinical Information
No Development Reported
Curated Selection
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