FAK-IN-19
FAK-IN-19 (ligand3) is an inhibitor in a co-crystal structure with FAK. FAK-IN-19 has anticancer effects[1].
Product Specifications
CAS Number
863599-15-9
UNSPSC
12352005
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fak-in-19.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC(C=C1NC2=NC3=C(C=N2)C=CN3C4=NC=CC=C4)=C(C(OC)=C1)OC
Molecular Formula
C20H19N5O3
Molecular Weight
377.40
References & Citations
[1]Jiu-Yu Zhan, et al. Exploring the interaction between human focal adhesion kinase and inhibitors: a molecular dynamic simulation and free energy calculations. J Biomol Struct Dyn. 2016 Nov;34 (11) :2351-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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