DENV-IN-12
DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines[1].
Product Specifications
CAS Number
2581065-80-5
UNSPSC
12352005
Target
Dengue Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/denv-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CC=C([C@@H]2C3)N1C[C@@H]3CN(C)C2=S
Molecular Formula
C12H14N2OS
Molecular Weight
234.32
References & Citations
[1]Lin CS, et al. Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease. Bioorg Med Chem Lett. 2024 Jan 18;99:129623.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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