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DENV-IN-12

DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines[1].

Product Specifications

CAS Number

2581065-80-5

UNSPSC

12352005

Target

Dengue Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/denv-in-12.html

Solubility

10 mM in DMSO

Smiles

O=C1C=CC=C([C@@H]2C3)N1C[C@@H]3CN(C)C2=S

Molecular Formula

C12H14N2OS

Molecular Weight

234.32

References & Citations

[1]Lin CS, et al. Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease. Bioorg Med Chem Lett. 2024 Jan 18;99:129623.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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