CJ28

CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis[1].

Product Specifications

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cj28.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NC2=CC=CC=C2N1)NC3=CC(Br)=CC=C3

Molecular Formula

C14H11BrN4O

Molecular Weight

331.17

References & Citations

[1]Kim SH, et al. Transcriptomic data of human adrenocortical NCI-H295R cells treated with cortisol biosynthesis inhibitors. Data Brief. 2023 Dec 12;52:109948.