CJ28
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis[1].
Product Specifications
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cj28.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC2=CC=CC=C2N1)NC3=CC(Br)=CC=C3
Molecular Formula
C14H11BrN4O
Molecular Weight
331.17
References & Citations
[1]Kim SH, et al. Transcriptomic data of human adrenocortical NCI-H295R cells treated with cortisol biosynthesis inhibitors. Data Brief. 2023 Dec 12;52:109948.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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