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EP3 antagonist 5

EP3 antagonist 5 (Compound 22) is an EP3 receptor antagonist with an IC50 value of 67 nM[1].

Product Specifications

CAS Number

499147-44-3

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ep3-antagonist-5.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC1=CC=C(C=C1C(NC(C2=CC=C(C(F)=C2)C)CC(C)C)=O)COC3=CC=CC=C3

Molecular Formula

C29H32FNO4

Molecular Weight

477.57

References & Citations

[1]Asada M, et al. 3- (2-Aminocarbonylphenyl) propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 2: Optimization of the side chains to improve in vitro and in vivo potencies[J]. Bioorganic & medicinal chemistry, 2010, 18 (4) : 1641-1658.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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