PR antagonist 1
PR antagonist 1 (compound 8) is a selective progesterone receptor (PR) antagonist, and can be used for the research of a variety of progesterone-related diseases and disorders such as endometriosis and uterine fibroids[1].
Product Specifications
CAS Number
936345-34-5
UNSPSC
12352005
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/pr-antagonist-1.html
Purity
99.71
Solubility
10 mM in DMSO
Smiles
N#CC1=C(C)C=C(OC2=C(C3CC3)N(CS(=O)(C)=O)N=C2C)C=C1C
Molecular Formula
C18H21N3O3S
Molecular Weight
359.44
References & Citations
[1]Paul A, et al. Development of a Practical Synthesis of the Progesterone Receptor Antagonist 4-{[3-Cyclopropyl-1- (mesylmethyl) -5-methyl-1H-pyrazol-4-yl]oxy}-2,6-dimethylbenzonitrile, Organic Process Research & Development 2009 13 (5), 848-853.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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