RO7075573

RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections[1][2].

Product Specifications

CAS Number

2097284-11-0

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ro7075573.html

Solubility

10 mM in DMSO

Smiles

CN(C([C@@H](NC([C@@H]1CCCN)=O)CCCCN)=O)[C@H](C(NCC(C(SC2=NC=CC=C2CN1)=C3Cl)=C(C=C3)Cl)=O)CC4=CNC5=CC=CC=C45

Molecular Formula

C36H44Cl2N8O3S

Molecular Weight

739.76

References & Citations

[1]Pahil KS, et al. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature. 2024 Jan 3.|[2]Zampaloni C, et al. A novel antibiotic class targeting the lipopolysaccharide transporter. Nature. 2024 Jan;625 (7995) :566-571.