K2-B4-5e
Product Specifications
UNSPSC Description
Target Antigen
Androgen Receptor; Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics;PROTAC;Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/k2-b4-5e.html
Solubility
10 mM in DMSO
Smiles
O=C(C[C@@H]1N=C(C2=C(N3C(C)=NN=C13)SC(C)=C2C)C4=CC=C(C=C4)Cl)NC5=CC=C(C=C5)C6=CC=C(C=C6)C(N7CCC8=C(N(C(C(CC(C)C)=C8)=O)C9=CN(C(C=C9)=O)CC(OC)=O)C7)=O
Molecular Weight
949.51
References & Citations
[1]Christopher M Hickey, et al. Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat Struct Mol Biol. 2024 Jan 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157491/K2-B4-5e-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157491/
Clinical Information
No Development Reported
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