α-Glucosidase-IN-47

α-Glucosidase-IN-47 (compound 8H) is a non-competitive α-glucosidase (α-glucosidase) inhibitor with IC50 value is 38.2 μM and Ki value is 38.2 μM. α-Glucosidase-IN-47 can be used in diabetes research.[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-47.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(F)C=C1)CSC2=NC3=CC=CC=C3C=C2C4=NC5=CC=CC=C5S4

Molecular Formula

C24H16FN3OS2

Molecular Weight

445.53

References & Citations

[1]Ghomi MK, et al. Synthesis, in vitro potency of inhibition, enzyme kinetics and in silico studies of quinoline-based α-glucosidase inhibitors. Sci Rep. 2024 Jan 4;14 (1) :501.