α-Glucosidase-IN-46

α-Glucosidase-IN-46 is a potent α-glucosidase inhibitor with an IC50 of 26.0 μM. α-Glucosidase-IN-46 can be used for the research of type 2 diabetes[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-46.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(CC)C=C1)COC2=CC=C(/C=N/NC(C3=CC(C4=CC=C(OC)C=C4)=NC5=CC=CC=C35)=O)C=C2OC

Molecular Formula

C35H32N4O5

Molecular Weight

588.65

References & Citations

[1]Hamedifar H, et al. Aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamides as potent α-glucosidase inhibitors; molecular dynamics, kinetic and structure-activity relationship studies. Sci Rep. 2024 Jan 3;14 (1) :388.