Anticancer agent 185

Anticancer agent 185 (compound 9d) is a glycohybrid derivative of pyrazolopyrimidine [1,5-a]. Anticancer agent 185 has good anti-breast cancer activity. Anticancer agent 185 shows good cytotoxic activity against MCF-7 cells with IC50 value of 15.3 μM[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-185.html

Solubility

10 mM in DMSO

Smiles

O=C(C)O[C@H]([C@H]([C@@H]1OC(C)=O)OC(C)=O)[C@@H](O[C@@H]1COC(C)=O)N2C=C(N=N2)COC3=CC(C4=CC=C(C=C4)Cl)=NC5=CC=NN53

Molecular Formula

C29H29ClN6O10

Molecular Weight

657.03

References & Citations

[1]Tiwari G, et al. Copper-catalyzed synthesis of pyrazolo[1,5-a]pyrimidine based triazole-linked glycohybrids: mechanistic insights and bio-applications. Sci Rep. 2024 Jan 4;14 (1) :529.