DPI-2016

DPI-2016 is a antibacterial agent. DPI-2016 shows improved bactericidal activity (MIC, 0.25-8 μg/mL) against all bacterial strains compared to the aztreonam (HY-B0129) (MIC, 16->64 μg/mL) [1].

Product Specifications

CAS Number

[2760731-35-7]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dpi-2016.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](O/N=C(C(N[C@H]1C(C)(C)N(OS(=O)(O)=O)C1=O)=O)/C2=C(SC(N)=N2)C)COC3=CC=C(C(N[C@@H]4CCNC4)=N)C=C3)=O

Molecular Formula

C25H32N8O10S2

Molecular Weight

668.70

References & Citations

[1]Zhai L, et al. Improved synthesis and evaluation of preclinical pharmacodynamic parameters of a new monocyclic β-lactam DPI-2016. Bioorg Med Chem Lett. 2024 Jan 8:129615.