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AChE-IN-53

AChE-IN-53 (Compound I-52) is a potent NMDAR inhibitor, which is a compound with favorable behavioral and neuroprotective effects[1].

Product Specifications

CAS Number

[2807436-94-6]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-53.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=CC=C1OC2=CC=C3N=C4CCCC4=C(C3=C2)N

Molecular Formula

C19H18N2O2

Molecular Weight

306.36

References & Citations

[1]Misiachna A, et al. Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition. Eur J Med Chem. 2024 Jan 7;266:116130.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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