Antiparasitic agent-21
Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC50 of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiparasitic-agent-21.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=NC=C(OC)C=C1NCC2=CC=C(C(C)(C)C)C=C2
Molecular Formula
C18H22N2O3
Molecular Weight
314.38
References & Citations
[1]Pomeroy J M, et al. Synthesis and Evaluation of Benzylamine Inhibitors of Neuropathogenic Naegleria fowleri “Brain-Eating” Amoeba[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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