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Antiparasitic agent-21

Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC50 of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antiparasitic-agent-21.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=NC=C(OC)C=C1NCC2=CC=C(C(C)(C)C)C=C2

Molecular Formula

C18H22N2O3

Molecular Weight

314.38

References & Citations

[1]Pomeroy J M, et al. Synthesis and Evaluation of Benzylamine Inhibitors of Neuropathogenic Naegleria fowleri “Brain-Eating” Amoeba[J]. ACS Medicinal Chemistry Letters, 2023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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