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[Ru (phen) 2 (4-Me-Sal) ]BF4

[Ru (phen) 2 (4-Me-Sal) ]BF4 (compound 10), a Ru (II) -based polypyridyl complexe, displays outstanding antiproliferative activity against drug-sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells (IC50=0.52 μM and 5.56 μM, respectively) [1].

Product Specifications

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ru-phen-2-4-me-sal-bf4.html

Solubility

10 mM in DMSO

Smiles

CC1=CC(O[Ru]23([N]4=C5C(C=CC6=C5[N]2=CC=C6)=CC=C4)([N]7=CC=CC8=C7C9=[N]3C=CC=C9C=C8)O=C%10)=C%10C=C1.[F-][B+3]([F-])([F-])[F-].[+]

Molecular Formula

C32H23BF4N4O2Ru-

Molecular Weight

683.43

References & Citations

[1]Maryam Taghizadeh Shool, et al. Investigating the Cytotoxicity of Ru (II) Polypyridyl Complexes by Changing the Electronic Structure of Salicylaldehyde Ligands. Inorg Chem. 2023 Dec 29.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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