CBR1-IN-3
CBR1-IN-3 (compound 13h) is a potent inhibitor of carbonyl reductase 1 (CBR1), with IC50 value of 0.034 μM[1].
Product Specifications
CAS Number
891101-69-2
UNSPSC
12352005
Target
NADPH Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cbr1-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=N)=CC2=C(O1)C(O)=CC=C2)NC3=CC=CC=C3Cl
Molecular Formula
C16H11ClN2O3
Molecular Weight
314.72
References & Citations
[1]Dawei Hu, et al. Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1. Org Biomol Chem. 2015 Jul 21;13 (27) :7487-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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