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CBR1-IN-3

CBR1-IN-3 (compound 13h) is a potent inhibitor of carbonyl reductase 1 (CBR1), with IC50 value of 0.034 μM[1].

Product Specifications

CAS Number

891101-69-2

UNSPSC

12352005

Target

NADPH Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cbr1-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C(C1=N)=CC2=C(O1)C(O)=CC=C2)NC3=CC=CC=C3Cl

Molecular Formula

C16H11ClN2O3

Molecular Weight

314.72

References & Citations

[1]Dawei Hu, et al. Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1. Org Biomol Chem. 2015 Jul 21;13 (27) :7487-99.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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