AChE/Aβ-IN-3
AChE/Aβ-IN-3 (compound AM5) is a dual inhibitor of AChE and Amyloid-β aggregation with IC50 values of 1.29 and 4.93 μM, respectively. AChE/Aβ-IN-3 has antioxidant properties that scavenge ROS and restore their normal levels. AChE/Aβ-IN-3 can be used in the study of neurological diseases, such as Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β; Cholinesterase (ChE) ; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-aβ-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(C(F)(F)F)=C1)CN2CCN(C3=CC(NC4=C3C=CC=C4)=O)CC2
Molecular Formula
C22H21F3N4O2
Molecular Weight
430.42
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Frequently Asked Questions
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