PppApA
PppApA is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA is formed by conjugation between two molecules of ATP[1].
Product Specifications
CAS Number
17730-98-2
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pppapa.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1OP(OC[C@H]2O[C@@H](N3C4=NC=NC(N)=C4N=C3)[C@@H]([C@@H]2O)O)(O)=O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O)N5C6=NC=NC(N)=C6N=C5
Molecular Formula
C20H28N10O19P4
Molecular Weight
836.39
References & Citations
[1]Kasi Manikandan, et al. Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis. PLoS One. 2014 Jan 23;9 (1) :e86096.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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