HDAC6-IN-30
Product Specifications
UNSPSC Description
HDAC6-IN-30 (compound 8g) is a selective HDAC6 inhibitor with the IC50 21 nM, and increase cell protein acetylation levels[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-30.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)C(C=C1)=CC=C1CN(C(C2=CC=CC=C2)=O)CC3=CC=CC=C3
Molecular Weight
360.41
References & Citations
[1]Jha S, et al. Design, synthesis, and biological evaluation of HDAC6 inhibitors targeting L1 loop and serine 531 residue. Eur J Med Chem. Published online December 20, 2023.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157436/HDAC6-IN-30-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157436/
Clinical Information
No Development Reported
Curated Selection
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