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25N-N1-Nap

25N-N1-Nap (compound 16) is a β-arrestin-biased 5-HT2A agonist. 25N-N1-Nap antagonizes phencyclidine induced hyperactivity in Male C57BL/6 J mice[1].

Product Specifications

CAS Number

2865185-31-3

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/25n-n1-nap.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(CCNCC2=C3C=CC=CC3=CC=C2)=C(C=C1[N+]([O-])=O)OC

Molecular Formula

C21H22N2O4

Molecular Weight

366.41

References & Citations

[1]Wallach J, et al. Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. Nat Commun. 2023;14 (1) :8221. Published 2023 Dec 15. |[2]Wallach J, et al. Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. Nat Commun. 2023;14 (1) :8221. Published 2023 Dec 15.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor

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