25N-N1-Nap
25N-N1-Nap (compound 16) is a β-arrestin-biased 5-HT2A agonist. 25N-N1-Nap antagonizes phencyclidine induced hyperactivity in Male C57BL/6 J mice[1].
Product Specifications
CAS Number
2865185-31-3
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/25n-n1-nap.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(CCNCC2=C3C=CC=CC3=CC=C2)=C(C=C1[N+]([O-])=O)OC
Molecular Formula
C21H22N2O4
Molecular Weight
366.41
References & Citations
[1]Wallach J, et al. Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. Nat Commun. 2023;14 (1) :8221. Published 2023 Dec 15. |[2]Wallach J, et al. Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. Nat Commun. 2023;14 (1) :8221. Published 2023 Dec 15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Frequently Asked Questions
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