FL77-24
FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, [1].
Product Specifications
CAS Number
[2413582-39-3]
Product Name Alternative
7- (4-Ethylphenyl) -FL118
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fl77-24.html
Solubility
10 mM in DMSO
Smiles
CC[C@]1(C(OCC2=C1C=C3C4=NC5=C(C(C6=CC(OC)=CC(OC)=C6)=C4CN3C2=O)C=C7OCOC7=C5)=O)O
Molecular Formula
C29H24N2O8
Molecular Weight
528.51
References & Citations
[1]Wenchao Wang, et al. Structure-Activity Relationship of FL118 Platform Position 7 Versus Position 9-Derived Compounds and Their Mechanism of Action and Antitumor Activity. J Med Chem. 2023 Dec 28;66 (24) :16888-16916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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