Anti-TNBC agent-5
Anti-TNBC agent-5 (compound 10C) is a triple-negative breast cancer (TNBC) inhibitor with good stability and pharmacokinetic properties. anti-TNBC agent-5 exhibits antiproliferative activity against a variety of cancer cells. anti-TNBC agent-5 can also effectively inhibit TNBC lung metastasis activity in the MDA-MB-231 xenograft model. anti-TNBC agent-5 can be used in cancer research[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352211
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anti-tnbc-agent-5.html
Solubility
10 mM in DMSO
Smiles
Cl[Pt]([NH3])(OC(CCC(N1CCN(CC1)/[N+]([O-])=N/OCC#C)=O)=O)(OC(NCCCCCCCCCCCC)=O)([NH3])Cl
Molecular Formula
C24H47Cl2N7O7Pt
Molecular Weight
811.66
References & Citations
[1]Zhang C, et al. Development of Integrated Bioorthogonal Self-Catalyzed NO Donor/Platinum (IV) Prodrugs for Synergistical Intervention against Triple-Negative Breast Cancer. J Med Chem. 2023 Dec 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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