Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan
Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan is a drug-linker conjugate for ADC (ADC Cytotoxin: Exatecan) [1].
Product Specifications
CAS Number
[2699066-62-9]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclooctyne-o-amido-peg4-vc-pab-gly-gly-nh-o-co-exatecan.html
Purity
97.31
Solubility
10 mM in DMSO
Smiles
O=C(COC1CCCCCC#C1)NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C2)=CC=C2COC(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
Molecular Formula
C69H90FN11O19
Molecular Weight
1396.51
References & Citations
[1]Masuda Takeshi, et al. Preparation of antibody-drug conjugates for cancer therapy. Patent WO2014057687.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
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