hMAO-B-IN-7
Product Specifications
UNSPSC Description
hMAO-B-IN-7 (compound 11n) is a potent and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B), with the IC50 value of 0.79±0.05 μM. hMAO-B-IN-7 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1].
Target Antigen
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hmao-b-in-7.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(C=CN1CCN2C(C3=CC=C(C=C3C2=O)OCC4=CC=C(C=C4)F)=O)=O)O
Molecular Weight
422.41
References & Citations
[1]Xi Zhu, et al. Exploration of the novel phthalimide-hydroxypyridinone derivatives as multifunctional drug candidates against Alzheimer’s disease. Bioorg Chem. 2023 Dec:141:106817.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157400/hMAO-B-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157400/
Clinical Information
No Development Reported
CAS Number
2955577-14-5
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