HMAO-B-IN-7

HMAO-B-IN-7 (compound 11n) is a potent and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B), with the IC50 value of 0.79±0.05 μM. hMAO-B-IN-7 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1].

Product Specifications

CAS Number

[2955577-14-5]

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hmao-b-in-7.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C(C=CN1CCN2C(C3=CC=C(C=C3C2=O)OCC4=CC=C(C=C4)F)=O)=O)O

Molecular Formula

C23H19FN2O5

Molecular Weight

422.41

References & Citations

[1]Xi Zhu, et al. Exploration of the novel phthalimide-hydroxypyridinone derivatives as multifunctional drug candidates against Alzheimer’s disease. Bioorg Chem. 2023 Dec:141:106817.