EeAChE/eqBuChE-IN-1
EeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3 μM and 0.81 μM, respectively. eeAChE/eqBuChE-IN-1 exhibits anti-inflammatory activity. eeAChE/eqBuChE-IN-1 also shows neuroprotective effect on Aβ25-35-induced PC12 cell injury[1].
Product Specifications
CAS Number
[2921654-26-2]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/eeache-eqbuche-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=C2C=CC=NC2=CC=C1)N(CC)CC
Molecular Formula
C14H16N2O2
Molecular Weight
244.29
References & Citations
[1]Chen h, et, al. Design, synthesis and evaluation of quinoline- O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :2169682.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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