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EeAChE/eqBuChE-IN-1

EeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3 μM and 0.81 μM, respectively. eeAChE/eqBuChE-IN-1 exhibits anti-inflammatory activity. eeAChE/eqBuChE-IN-1 also shows neuroprotective effect on Aβ25-35-induced PC12 cell injury[1].

Product Specifications

CAS Number

2921654-26-2

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/eeache-eqbuche-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(OC1=C2C=CC=NC2=CC=C1)N(CC)CC

Molecular Formula

C14H16N2O2

Molecular Weight

244.29

References & Citations

[1]Chen h, et, al. Design, synthesis and evaluation of quinoline- O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :2169682.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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