HDAC-IN-67
Product Specifications
UNSPSC Description
HDAC-IN-67 (compound 27f) is an HDAC inhibitor against HDAC1 and HDAC6, with IC50 values of 22 nM and 8 nM, respectively. HDAC-IN-67 inhibits cell proliferation and induces cell apoptosis. HDAC-IN-67 exhibits antitumor activity[1].
Target Antigen
Apoptosis; HDAC
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-67.html
Solubility
10 mM in DMSO
Smiles
ONC(CCCCCCC(N1CCN(CC1)CC([C@@H]2CC[C@](C=C)(C)[C@H](C(CN3N=CC=C3)=C)C2)=C)=O)=O
Molecular Weight
525.73
References & Citations
[1]Gao Y,et al., Design, synthesis and biological evaluation of novel histone deacetylase (HDAC) inhibitors derived from β-elemene scaffold. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2195991.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157385/HDAC-IN-67-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157385/
Clinical Information
No Development Reported
CAS Number
2821923-75-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
