CYP51-IN-15
CYP51-IN-15 (9B) is a BBB penetrated Naegleria fowleri-specific CYP51 inhibitor, with an EC50 of 1.5 μM[1].
Product Specifications
CAS Number
3034186-60-9
UNSPSC
12352005
Target
Cytochrome P450; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cyp51-in-15.html
Solubility
10 mM in DMSO
Smiles
FC(C1=CC(CO[C@@H](C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)=CC=C1)(F)F
Molecular Formula
C19H15Cl2F3N2O
Molecular Weight
415.24
References & Citations
[1]Vandna Sharma, et al. Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors. J Med Chem. 2023 Dec 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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