WDR5-IN-7

WDR5-IN-7 (Compound 22) is an orally bioavailable benzoxazepinone-based WD repeat domain 5 (WDR5) inhibitor. WDR5-IN-7 can be used for the research of anti-cancer[1].

Product Specifications

CAS Number

[3032761-31-9]

UNSPSC

12352005

Target

WDR5

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wdr5-in-7.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(OCCN1[C@@H]3C4=CC(OC)=CN=C4CCC3)C(C5=CN(C)N=C5C(F)(F)F)=CC(CN6C=NC=C6)=C2

Molecular Formula

C28H27F3N6O3

Molecular Weight

552.55

References & Citations

[1]Teuscher KB, et al. Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors. J Med Chem. 2023 Dec 12.