WDR5-IN-7
WDR5-IN-7 (Compound 22) is an orally bioavailable benzoxazepinone-based WD repeat domain 5 (WDR5) inhibitor. WDR5-IN-7 can be used for the research of anti-cancer[1].
Product Specifications
CAS Number
[3032761-31-9]
UNSPSC
12352005
Target
WDR5
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wdr5-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OCCN1[C@@H]3C4=CC(OC)=CN=C4CCC3)C(C5=CN(C)N=C5C(F)(F)F)=CC(CN6C=NC=C6)=C2
Molecular Formula
C28H27F3N6O3
Molecular Weight
552.55
References & Citations
[1]Teuscher KB, et al. Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors. J Med Chem. 2023 Dec 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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