HMAO-B-IN-6
HMAO-B-IN-6 (compound 17d) is a potent and selective inhibitor of hMAO-B with an IC50 of 67.02 nM. hMAO-B-IN-6 significantly improves Scopolamine -induced cognitive impairment in AD mice[1].
Product Specifications
CAS Number
2764830-43-3
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hmao-b-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C1C(O)=C(C)N(CCNCC2=COC3=C(C=CC(OC)=C3)C2=O)C=C1
Molecular Formula
C19H20N2O5
Molecular Weight
356.37
References & Citations
[1]Zhang C, et al. Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :100-117.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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