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HMAO-B-IN-6

HMAO-B-IN-6 (compound 17d) is a potent and selective inhibitor of hMAO-B with an IC50 of 67.02 nM. hMAO-B-IN-6 significantly improves Scopolamine -induced cognitive impairment in AD mice[1].

Product Specifications

CAS Number

2764830-43-3

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hmao-b-in-6.html

Solubility

10 mM in DMSO

Smiles

O=C1C(O)=C(C)N(CCNCC2=COC3=C(C=CC(OC)=C3)C2=O)C=C1

Molecular Formula

C19H20N2O5

Molecular Weight

356.37

References & Citations

[1]Zhang C, et al. Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :100-117.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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