HCAI/II-IN-7
HCAI/II-IN-7 (compound 1F) is a potent carbonic anhydrase (CA) inhibitor with Ki values of 23 nM, 44 nM and 20.57 µM for hCA-I, hCA-II and bovine CA, respectively[1].
Product Specifications
CAS Number
[14204-32-1]
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hcai-ii-in-7.html
Purity
99.80
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=CC=CC=C2C(N1SC3=CC=C(C=C3)Br)=O
Molecular Formula
C14H8BrNO2S
Molecular Weight
334.19
References & Citations
[1]Hasan Yakan, et al. Inhibitory effects of sulfenimides on human and bovine carbonic anhydrase enzymes. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :2194573.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA; CA II; CA I
Available Sizes
Curated Selection
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