c-Met-IN-21
Product Specifications
UNSPSC Description
c-Met-IN-21 (compound 54) is a c-met inhibitor with an IC50 value of 0.45 nM, and shows anti-tumor efficacy in vivo[1].
Target Antigen
c-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-met-in-21.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=NN=C2C=CC(C(C=C3CC4)=CC=C3N(CC(N5CCN(C(C)C)CC5)=O)C4=O)=NN12)C6=CC=C7C(C=CC=N7)=C6
Molecular Weight
610.66
References & Citations
[1]Min W, et al. Discovery of potent and selective c-Met inhibitors for MET-amplified hepatocellular carcinoma treatment. Eur J Med Chem. Published online December 5, 2023.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157302/c-Met-IN-21-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157302/
Clinical Information
No Development Reported
CAS Number
3025958-01-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
IHUCD38ARCHISLY50UG 50 µg
CD38 Active Recombinant Protein C-His Tag Lyophilized 50ug
Ask
View Details