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Anti-TNBC agent-4

Anti-TNBC agent-4 (compound 7) exhibits highly inhibitory activity against different TNBC cells with IC50s from 0.37 μM to 1.52 μM. anti-TNBC agent-4 inhibits IKKβ mediated phosphorylation of IκB and p65. anti-TNBC agent-4 induces TNBC cells apoptosis[1].

Product Specifications

CAS Number

3027501-51-2

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anti-tnbc-agent-4.html

Solubility

10 mM in DMSO

Smiles

C[C@@]1(CC/C=C2COC3=CC=C(C(SS4)=CC4=S)C=C3)[C@@](O1)([H])[C@](OC5=O)([H])[C@](CC/2)([H])C5=C

Molecular Formula

C24H24O4S3

Molecular Weight

472.64

References & Citations

[1]Chen T, et al. Synthesis of melampomagnolide B derivatives as potential anti-Triple Negative Breast Cancer agents. Eur J Med Chem. 2023 Dec 3;264:116024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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