J10-1
J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB1*0401) ) and promotes peptide binding to MHC II, which can be used in the study of immune regulation[1].
Product Specifications
CAS Number
1069110-72-0
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/j10-1.html
Purity
99.9200
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(C=CC(NC(CC1=C(C(O)=O)NC2=C(F)C(F)=C(F)C=C12)=O)=C3)=C3Cl
Molecular Formula
C17H9Cl2F3N2O3
Molecular Weight
417.17
References & Citations
[1]Call M J. Small molecule modulators of MHC class II antigen presentation: mechanistic insights and implications for therapeutic application[J]. Molecular Immunology, 2011, 48 (15-16) : 1735-1743.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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