Brazilin-7-acetate
Brazilin-7-acetate (B-7-A) is an inhibitor of α-synuclein (α-Syn) aggregates. Brazilin-7-acetate inhibits the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress. Brazilin-7-acetate can be used in the research of Parkinson's disease[1].
Product Specifications
UNSPSC
12352005
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/brazilin-7-acetate.html
Solubility
10 mM in DMSO
Smiles
O[C@]12COC3=C(C=CC(OC(C)=O)=C3)[C@@]1([H])C(C=C(C(O)=C4)O)=C4C2
Molecular Formula
C18H16O6
Molecular Weight
328.32
References & Citations
[1]Zhan Cui, et al. Brazilin-7-acetate, a novel potential drug of Parkinson's disease, hinders the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress. European Journal of Medicinal Chemistry. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation
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