HDAC1 Degrader-1
Product Specifications
UNSPSC Description
HDAC1 Degrader-1 (compound 1a) is an HDAC1 degrader with anticancer activity. HDAC1 Degrader-1 significantly reduces HDAC1 levels in MM.1S multiple myeloma cells[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/hdac1-degrader-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCCCCC(NO)=O)C1=CC=C(NC(CC2(C3)C[C@@H](C4)C[C@H]3C[C@@H]4C2)=O)C=C1
Molecular Weight
455.59
References & Citations
[1]Feller F et al. Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157216/HDAC1-Degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157216/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
CX62-500ug 500 µg
Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 (C-Fc)
Ask
View Details