HDAC1 Degrader-1
HDAC1 Degrader-1 (compound 1a) is an HDAC1 degrader with anticancer activity. HDAC1 Degrader-1 significantly reduces HDAC1 levels in MM.1S multiple myeloma cells[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac1-degrader-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCCCCC(NO)=O)C1=CC=C(NC(CC2(C3)C[C@@H](C4)C[C@H]3C[C@@H]4C2)=O)C=C1
Molecular Formula
C26H37N3O4
Molecular Weight
455.59
References & Citations
[1]Feller F et al. Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
149501 50 µg
NALP14, Control Peptide (NACHT, LRR and PYD Domains-containing Protein 14, Nucleotide-binding Oligomerization Domain Protein 5, NALP14, NOD5)
Ask
View Details